The kidneys play key roles in body function, not only by filtering the blood and getting rid of waste products, but by balancing levels of electrolytes in the body, controlling blood pressure, and stimulating the production of red blood cells.
The kidneys monitor the amount of body fluid, the concentrations of electrolytes like sodium and potassium, and balance of the body. The kidneys filter waste products in the blood like blood urea nitrogen or BUN and creatinine or Cr.
If a person is dehydrated, the kidneys will hold onto as much water as possible and the urine becomes concentrated. When adequate water is present in the body, the urine is much more diluted and becomes clear.
With rhabdomyolysis, there is significant muscle breakdown in the body, and the degeneration products of muscle fibers clog the filtering system of the kidneys. Often occurring because of trauma and crush injuries, it can also be caused by some medications used to treat high cholesterol.
If kidney disease gets worse, wastes can build to high levels in your blood and make you feel sick. You may develop complications like high blood pressure, anemia, weak bones, poor nutritional health, and nerve damage. Also, kidney disease increases your risk of having heart and blood vessel disease. These problems may happen slowly over a long period of time. Early detection and treatment can often keep chronic kidney disease from getting worse. When kidney disease increases, it may eventually lead to kidney failure, requiring dialysis or kidney transplantation to maintain life.
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