Answers to Three Questions About Topamax and Pregnancy

If you have seizures and want to become pregnant then you have two very important interests to protect. Your ultimate concern is becoming a mother as safely as possible.

That means that your safety and that of your child must both be taken into account when making decisions about medications. We understand your concern and want to help provide you with the information that you need to make the decisions that are right for you and your baby.

To that end, we are providing you with some answers to questions that we commonly hear such as:

Is it Possible to Get Pregnant While Taking Topamax? Yes, Topamax does not prevent pregnancy despite the potential danger of Topamax neonate development.

Has There Been a Cleft Palate Topiramate Study? Yes, studies have been done that have linked Topiramate to a higher incidence of children born with cleft lips and cleft palates

What is the Percentage of Birth Defects While Taking Topamax While Pregnant? Children born to women who took Topamax during pregnancy have approximately a 1.4% of chance of being born with a cleft palate or cleft lip. While that may seem low, the risk is about 20 times higher for children born to mothers who took Topamax while pregnant as compared to children born to mothers who did not take anti-seizure medication. The risk is also elevated for children born to women taking Topamax as compared to other types of anti-seizure medication.

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Accordingly, it is important to talk to your doctor about the risks and to learn what to do if your child is born with a cleft palate or cleft lip.

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