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Antidepressants – Paxil Birth Defects, SSRI Drugs
Paxil is in a class of drugs known as SSRI. Paxil is used to treat MDD, panic disorder, social anxiety disorder, generalized anxiety disorder, obsessive compulsive disorder, and (PTSD) post traumatic stress disorder.
Paxil is in a pregnancy drug category D.
Epidemiological studies have shown that infants exposed to Paxil in the first trimester of pregnancy have an increased risk of congenital malformations, particularly cardiovascular malformations. A study based on Swedish national registry data demonstrated that infants exposed to Paxil during pregnancy had an increased risk of cardiovascular malformations.
Cardiac malformations of Paxil-exposed infants were primarily ventricular septal defexcts (VSD) and atrial septal defects (ASD). Septal defects range in severity from resolving spontaneously to requiring surgery.
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A separate retrospective U.S. study evaluated 5,956 infants of mothers who took antidepressants during the first trimester. This study showed a trend towards an increased risk for cardiovascular malformations from Paxil compared to other antidepressants Of the 12 Paxil-exposed infants with cardiovascular malformations, 9 had ventricular septal defects. This study also suggested an increased risk of overall major congenital malformations including cardiovascular defects for Paxil compared to other antidepressants.
If a woman becomes pregnant while taking Paxil, she should be advised of the potential harm to the fetus. Unless the benefits of Paxil far outweigh the risks for pregnant women or women who are thinking of getting pregnant or may accidentally get pregnant, consideration should be given to either switching to another antidepressant or discontinuing Paxil.
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Does your baby suffer from heart malformations? Are you drowning in a sea of medical expenses? Were you taking Paxil while pregnant? Ask Anapol Schwartz about your legal options in filing a claim against the unsafe SSRI drug Paxil.
