Jaw Infections/Osteoporosis Drugs
Osteonecrosis is a disease in which the blood supply to the bone is temporarily or permanently cut off leading to a collapse of the bone. Signs include jaw pain, swelling of the soft tissue, infection, drainage, loosening of the teeth and exposed bone.
The exact cause of jaw osteonecrosis in patients taking bisphosphonates is unknown. However, the condition appears to be linked to trauma associated with dental surgery, tooth extraction, poorly fitting dentures. Risk for jaw osteonecrosis is highest among those using the IV form of bisphosphonates. According to the American Dental Association, when bisphosphonates are given intravenously, the drug goes right into the circulatory system and over 50 percent of the dose can be incorporated into the bone. Only about one percent of an oral dose is absorbed into the body.
Patients are recommended to have a thorough dental examination and correcting tooth or gum problems before starting bisphosphonate therapy. Patients should also inform their dentist if they are already taking bisphosphonates. Once bisphosphonates are started, patients must pay extra attention to good oral hygiene. Dental examinations are also recommended every three months. (WSOC TV)
