Actos and Bladder Cancer

What is bladder cancer? What causes bladder cancer?

Bladder cancer is any of several types of malignant growths of the urinary bladder. Bladder cancer typically causes blood in the urine.

Other possible symptoms include pain during urination, frequent urination or feeling the need to urinate without actually urinating. However, these symptoms are not specific to bladder cancer.

In the United States, bladder cancer is the fourth most common type of cancer in men and the ninth most common cancer in women.

Here are the different stages of bladder cancer:

• Stage 0: Cancer cells are found only on the inner lining of the bladder.
• Stage I: Cancer cells have proliferated to the layer beyond the inner lining of the urinary bladder but not to the muscles of the urinary bladder.
• Stage II: Cancer cells have proliferated to the muscles in the bladder wall but not to the fatty tissue that surrounds the urinary bladder.
• Stage III: Cancer cells have proliferated to the fatty tissue surrounding the urinary bladder and to the prostate gland, vagina, or uterus, but not to the lymph nodes or other organs.
• Stage IV: Cancer cells have proliferated to the lymph nodes, pelvic or abdominal wall, and/or other organs.
• Recurrent: Cancer has recurred in the urinary bladder or in another nearby organ after having been treated.

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What causes bladder cancer? What caused your bladder cancer?

• Tobacco smoking is the main known contributor to urinary bladder cancer
• Not drinking enough water
• Genetic
• Chemotherapy and radiation therapy
• Long-term use of the chemotherapy drug Cytoxan which can irritate the bladder and increase the risk of bladder cancer. People taking this drug are often told to drink plenty of fluids to help
• Excessive grilled and/or barbequed meat and fat
• Occupational exposure to carcinogens such as bus drivers, motor vehicle mechanics, rubber workers, leather workers, blacksmiths, machine mechanics, gardeners/landscapers, farm workers, and hair dressers
• Toxic substances such as asbestos, chlorinated solvents, combustion, creosote, diesel engine exhaust, dust, leather, mineral oils, pesticides, paint, dyes in textiles/ hair dyes/printing, polycyclic aromatic hydrocarbons – byproducts of fuels burning
• Certain medications, such as the diabetes drug Actos, manufactured by Takeda Pharmaceuticals, have also been associated with causing bladder cancer.

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